Mosaic Pattern Formations in Multicellular Chemical Systems
نویسنده
چکیده
A 2-dimensional array of coupled Brusselators cells is studied numerically. A variety of stationary patterns are obtained depending on the coupling strength of an activator and an inhibitor. Mosaic patterns of different motifs, in a very complicated spatial arrangement, are discovered. The mechanism that leads to the formation of the mosaic patterns consists of the formation of rings by an oscillatory chemical medium, the breaking of rings, and the interaction with the cellular chemical medium.
منابع مشابه
Differential and Cooperative Cell Adhesion Regulates Cellular Pattern in Sensory Epithelia
Animal tissues are composed of multiple cell types arranged in complex and elaborate patterns. In sensory epithelia, including the auditory epithelium and olfactory epithelium, different types of cells are arranged in unique mosaic patterns. These mosaic patterns are evolutionarily conserved, and are thought to be important for hearing and olfaction. Recent progress has provided accumulating ev...
متن کاملTransition from one- to two-dimensional development facilitates maintenance of multicellularity
Filamentous organisms represent an example where incomplete separation after cell division underlies the development of multicellular formations. With a view to understanding the evolution of more complex multicellular structures, we explore the transition of multicellular growth from one to two dimensions. We develop a computational model to simulate multicellular development in populations wh...
متن کاملA Feedback Quenched Oscillator Produces Turing Patterning with One Diffuser
Efforts to engineer synthetic gene networks that spontaneously produce patterning in multicellular ensembles have focused on Turing's original model and the "activator-inhibitor" models of Meinhardt and Gierer. Systems based on this model are notoriously difficult to engineer. We present the first demonstration that Turing pattern formation can arise in a new family of oscillator-driven gene ne...
متن کاملBacterial biofilms and their new control strategies in food industry
Biofilm is a multicellular layer of adherent bacteria surrounded by organic polymer matrix. The development of biofilms in food processing environments is a potential source of hazard for food safety and quality [1]. Food contact surfaces are commonly disinfected with different chemical compounds. However, corrosion and toxicity limit the use of these commercial disinfectants [2]. The risk will...
متن کاملCan we build synthetic, multicellular systems by controlling developmental signaling in space and time?
Using biological machinery to make new, functional molecules is an exciting area in chemical biology. Complex molecules containing both 'natural' and 'unnatural' components are made by processes ranging from enzymatic catalysis to the combination of molecular biology with chemical tools. Here, we discuss applying this approach to the next level of biological complexity -- building synthetic, fu...
متن کامل